The Tooth, the Whole Tooth, and nothing but the Tooth: the importance of publishing negative data.

You’ve worked hard for three years, poured your heart and soul into a project which has become the centre of your universe, only to find your data doesn’t tell the story you were hoping for… but is this really the bombshell it first seems? I spoke to Conor O’Boyle, a final year PhD student who … Continue reading The Tooth, the Whole Tooth, and nothing but the Tooth: the importance of publishing negative data.

Worming our way out of the allergy epidemic!

Author: Alex Bennett Parasitic worms are a particularly gruesome infection, and fortunately for much of the world’s population, they are largely things of the past. Yet, even a few hundred years ago worm infections were universal - Richard III, the king of England, suffered from a roundworm infection. Worms have been omnipresent among animals for … Continue reading Worming our way out of the allergy epidemic!

Researcher Spotlight: Ethan Du-Crow

Technology plays an integral role in almost every aspect of our lives and its capabilities are constantly developing. Technological advances in medicine in particular have had a huge impact. There is no doubt that the precision, accuracy, and efficiency of medical tasks has been vastly improved by implementing these technologies, but are there any risks to … Continue reading Researcher Spotlight: Ethan Du-Crow

Women in the breast screening programme: active and empowered decision-makers or passive recipients of the service? Which is better?

Author: Hannah Long As part of my PhD at the University of Manchester, I have undertaken a systematic review and synthesis of qualitative research of women’s experiences of having a false positive test result (a ‘false alarm’) in breast screening. These results occur when a woman’s routine screening exam comes back as inconclusive and she … Continue reading Women in the breast screening programme: active and empowered decision-makers or passive recipients of the service? Which is better?

Putting out the fire: Manchester leads the fight against neuroinflammation

Author: Jo Sharpe It is hard to avoid the sensational headlines popping up here, there, and everywhere: “Blocking brain inflammation 'halts Alzheimer's disease'”, “The foods that might help with dementia”, and my personal favourites “Dementia: Drinking wine can cut risk of brain inflammation” and “Turmeric health benefits: Curry spice could hold key to combating Alzheimer’s”. … Continue reading Putting out the fire: Manchester leads the fight against neuroinflammation

How can we limit the damage to the brain after a stroke?

Author: Paul Humphreys Stroke is the second leading cause of death worldwide and although survival rates are increasing year after year, the majority of stroke survivors live with a major disability as a result of severe brain damage. Ischemic stroke is the most common form of stroke where a blockage, or occlusion, in a blood … Continue reading How can we limit the damage to the brain after a stroke?

Can our body clock help to repair injuries or cure disease?

Author: Paul Humphreys The human body can be compared to a well-oiled machine with tissues acting as individual components that function both independently and harmoniously. However, this comparison is only apt if the hypothetical machine performs certain tasks more efficiently at certain times of day and shuts down completely if you attempt to leave it … Continue reading Can our body clock help to repair injuries or cure disease?

Research spotlight at Manchester: 3D Bioprinting

A considerable challenge for researchers that investigate human disease is to be able to accurately recreate the disease outside of the human body. Disease investigation in vitro, (or ‘in a dish’) is described as ‘disease modelling’ and generally involves isolating or generating diseased cells before subjecting them to various conditions. Disease models are an invaluable … Continue reading Research spotlight at Manchester: 3D Bioprinting